Moderna says new data shows its Covid vaccine is more than 90% effective against virus six months after second shot
- Moderna said its Covid-19 vaccine was more than 90% effective at protecting against Covid-19 and more than 95% effective against severe disease up to six months after the second dose.
- The new data includes cases through April 9 and evaluated over 900 cases of Covid-19, including more than 100 severe cases.
- The update brings Moderna a step closer to filling its vaccine for full U.S. approval.
Moderna's Covid-19 vaccine was more than 90% effective at protecting against Covid-19 and more than 95% effective against severe disease up to six months after the second dose, the company said Tuesday, citing updated data from its phase three clinical trial.
The update brings Moderna a step closer to filling its vaccine for full U.S. approval, a more rigorous review process to show the shot is safe and effective for its intended use. Once it gets full approval, Moderna can begin marketing the shots directly to consumers and selling them to individuals and private companies in the U.S.
The new data includes cases through April 9 and evaluated over 900 cases of Covid-19, including more than 100 severe cases, it said. The vaccine is currently authorized for emergency use by the Food and Drug Administration for people who are age 18 and older and the agency can always revoke the EUA at anytime. Moderna submitted only two months of follow-up safety data for the EUA. The FDA usually requires six months for full approval.
The company said its results are preliminary. Moderna said throughout the year it will share updated data on efficacy against asymptomatic infection as well as the persistence of antibodies.
The new data comes after a study published in the New England Journal of Medicine showed antibodies induced by the Moderna vaccine were still present six months after the second dose. It also comes after Pfizer said earlier this month its vaccine, which uses similar technology to Moderna's, was also shown to be highly effective six months after the second dose.
Isaac Bogoch, an infectious disease specialist who has sat on several drug data and safety monitoring board, called Moderna's update "amazing news," adding it's great to hear that both mRNA vaccines are highly effective at six months.
"I think it is fair to estimate that they will both have decent efficacy for many months beyond this," he said.
Moderna is still evaluating its vaccine in kids ages 17 and younger.
The company said Tuesday its trial testing adolescents between ages 12 to 17 is now fully enrolled with about 3,000 participants in the U.S.
It said its trial testing the shot on 6-month to 11-year-old children is currently enrolling. It expects to enroll 6,750 healthy pediatric participants in the U.S. and Canada. Like Pfizer's study, kids will begin by receiving a low dose of the vaccine before progressively moving to higher doses.
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